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Publications

Grainger Laboratory

Selected Publications

View Dr. Grainger’s NCBI bibliography here.

* denotes equal contribution
# denotes co-corresponding authors

Molina B*, Chavez J*, Grainger S. 2020. Zebrafish models of acute leukemias: Current models and future directions. Wiley Interdiscip Rev Dev Biol e400. 

Gumber D*, Do M*, Suresh Kumar N,  Wu CCN, Cruz LS, Grainger S, Carson D, Gaasterland T, Willert K, 2020. Selective activation of FZD7 promotes mesendodermal differentiation of human pluripotent stem cells. eLife 9:e63060.

Espanola SG, Song H, Ryu E, Saxena A, Kim ES, Manegold JE, Nasamran CA, Sahoo D, Oh CK, Bickers C, Shin U, Grainger S, Park YH, Pandolfo L, Kang MS, Kang S, Myung K, Cooper K, Yelon D, Lee Y, Traver D. 2020. Hematopoietic stem cell-dependent Notch transcription is mediated by P53 through the histone chaperone Supt16h. Nat Cell Bio 22:1411–1422.

Grainger S, Nguyen N, Richter J, Setayesh J, Lonquich B, Oon CH, Wozniak JM, Barahona R, Kamei C, Houston J, Carrillo-Terrazas M, Drummond I, Gonzalez D, Willert K, Traver D. 2019. EGFR confers exquisite specificity of Wnt9a-Fzd9b signaling in hematopoietic stem cell development. Nat Cell Bio 21(6):721–730.

Bickers C, Espanola S, Grainger S, Pouget C, Traver D. 2018. Comparison of snai2 morpholino and mutant phenotypes. PLoS One 13(9):e0202747.

Markmiller RL*, Schaffer AE*, Eggans VR, Zaki MS, Grainger S, Sathe S, Van Nostrand EL, Schlachetzki Z, Rosti B, Akizu N, Scott E, Heckman LD, Rosti RO, Dikoglu E, Gregor A, Guemez-Gamboa A, Musaec D, Mande R, Widjaja W, Shaw TL, Markmiller S, Marin-Valencia I, Foulds N, Dobyns WB, Chi N, Traver D, Spaccini L, Bova S, Gabriel SB, Gunel M, Valente EM, Bennett EJ, Yeo GW, Baas F, Lykke-Andersen J#, Gleeson JG#. 2017. Biallelic mutations in the 3’ exonuclease TOE1 cause Pontocerebellar Hypoplasia Type 7 and result in snRNA processing defects. Nat Genet 49(3):457–464.

Grainger S, Lonquich B, Oon CH, Nguyen N, Willert K#, Traver D#. 2017. CRISPR guide RNA validation in vitro. Zebrafish 14(4):383–386.

Grainger S*, Richter J*, Espin-Palazon R, Pouget C, Lonquich B, Wirth S, Grassme KS, Herzog W, Swift MR, Weinstein BM, Willert K#, Traver D#. 2016. Wnt9a is required for the aortic amplification of nascent hematopoietic stem cells. Cell Rep 17(6) 1595 –1606.

Hryniuk A*, Grainger S*, Savory JGA, Lohnes D, 2014. Cdx1 and Cdx2 function as tumor suppressors. J. Biol Chem 289(48):33343–33354.

Grainger S, Hryniuk A, Lohnes D. 2012. Cdx1 and Cdx2 exhibit transcriptional specificity in the intestine. PLoS One 8(1):e54757.

Lafontaine C*, Grainger S*, Hess BL, Béland M, Lohnes D. 2012. Cdx1 interacts physically with a subset of Hox proteins. Biochemistry J 51(48):9698–9705.

Hryniuk A, Grainger S , Savory JGA, Lohnes D. 2012. Cdx is required for maintenance of intestinal identity in the adult. Dev Biol 363:426–437.

Grainger S*, Lam J*, Savory JGA, Mears AJ, Rijli F, Lohnes D. 2011. Cdx regulates Dll1 in multiple lineages. Dev Biol 361, 1–11.

Grainger S, Savory JGA, Lohnes D. 2010. Cdx2 regulates patterning of the intestinal epithelium. Dev Biol 339:155–165.

Savory JGA, Pilon N, Grainger S, Sylvestre JR, Beland M, Houle M, Oh K, Lohnes D. 2009. Cdx1 and Cdx2 are functionally equivalent in vertebral patterning. Dev Biol 330:114–122.